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KMID : 0644120040170010129
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Journal of Oriental Gynecology
2004 Volume.17 No. 1 p.129 ~ p.137
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Effects of Cervi Pantotrichum Cornu on the Reproduction and in vitro Developmental Competence of Male Mice
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Oh Jae-Sung
Cho Jung-Hoon
Lee Kyung-Sub
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Abstract
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Objective : This study was conducted to investigate the effects of Cervi Pantotri chum Cornu (鹿茸) on the reproduction and in vitro developmental competence in male mice.
Materials and Methods : We administered the extract of Cervi Pantotrichum Cornu to 8-week and 18-week old male mice, once a day for 8 days. And we observed the count, the motility and the morphology of epididymal sperm from the male mice and in vitro fertilization and embryonic development of mouse oocytes. And also we examined the pregnancy and delivery of in vitro cultured blastocyst from the mice.
Results :There was no significant difference between the sperm count of treated group and that of control group in 8-week and 18-week-old mice. But the motility and morphology of epididymal sperm of treated group increased more than that of control group in 8-week and 18-week-old mice. The rate of the rate of fertilization in vitro and embryonic development of mouse oocytes of treated group increased more than that of control group in 8-week and 18-week-old mice. But the only morphologic change of epididymal sperm in 8-week old mice is statistically significant. There was no significant difference between the rate of pregnancy and delivery of in vitro cultured blastocyst from mice of Cervi Pantotrichum Cornu treated group and that of control group in both 8-week and 18-week old mice.
Conclusion :The result of this study had no statistically significance for a few number of experiment mice but shows that Cervi Pantotrichum Cornu has a effect on the motility, morphology of epididymal sperm from the male mice and in vitro fertilization and embryonic development of mouse oocytes. It is concluded that Cervi Pantotrichum Cornu has a effect on the improvement of virility in men.
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KEYWORD
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Cervi Pantotrichum Cornu, male mice, spermatogenesis, reproduction
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